A solid two-under 70 in the final round saw Matt Kuchar clinch the Players Championship on Sunday, while Geoff Ogilvy was the highest-ranked Australian in a tie for 12th.
Kuchar, who started the day a shot behind overnight leader Kevin Na, finished at 13 under at TPC Sawgrass in Florida, two shots clear of four players.
Scot Martin Laird and American trio Zach Johnson, Rickie Fowler and Ben Curtis tied for second.
English world number two Luke Donald finished with a six-under 66 to end up sixth at nine under.
Ogilvy, who was consistent throughout the PGA Tour event, carded a three-under 69 to be at six under.
Adam Scott (five under) tied for 15th, Marc Leishman (even par) was outright 45th, while Rod Pampling (three over) and Robert Allenby (four over) struggled in their final rounds.
Kuchar, whose victory was his fourth on the PGA Tour and first since August 2010, was thrilled to have beaten a field that included nine of the world's top 10 players.
"It's such an amazing feeling — playing amongst the game's best, to come out on top, to do it on Mother's Day ... it really is magical," he said.
After bogeying the first hole, Kuchar produced four birdies, and he held on despite a bogey on the par-three 17th.
Na, given a warning on Saturday for slow play, was quicker with his shots, but a four-over 76 in the final round left him at eight under and tied for seventh.
The American dropped four shots in five holes starting at the fifth to end his chances of challenging for the victory.
Alongside him at eight under were countryman Bo Van Pelt and Venezuelan Jhonattan Vegas, while American David Toms and Swede Carl Pettersson tied for 10th a further shot back.
Tiger Woods carded a one-over 73 in the final round to finish the tournament at one under and world number three Lee Westwood produced a five-over 77 to finish tied for 61st.